EasyScript Plus™ Reverse Transcriptase is a novel recombinant reverse transcriptase that exhibits much higher efficiency in the first strand cDNA synthesis from RNA templates with secondary structures and high GC contents. The EasyScript Plus™ Reverse Transcriptase is engineered to work under high temperatures (50°C-55°C), which can further facilitate to resolve the secondary structures and high GC problems of RNA. Due to this feature, full-length cDNA can be synthesized from RNA templates that are up to 12 kb.